Dicyclomine + Mefenamic Acid is a combination of two medicines: Dicyclomine and Mefenamic Acid. Dicyclomine is an anticholinergic which works by relaxing the muscles in the stomach and gut (intestine). It stops sudden muscle contractions (spasms), thereby relieving cramps, pain, bloating, and discomfort. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause abdominal pain and inflammation (swelling). Together, they relieve menstrual cramps and colicky pain.