Enteric Coated Pantoprazole Sodium & Sustained Release Domperidone Capsule
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Enteric Coated Pantoprazole Sodium & Sustained Release Domperidone Capsule
Introduction:
Enteric Coated Pantoprazole Sodium & Sustained Release Domperidone Capsule is a combination medication used to treat certain gastrointestinal conditions. It contains two active ingredients: Pantoprazole Sodium and Domperidone. The capsule formulates with an enteric coating to ensure proper release of the drugs in the digestive system, providing targeted effects and reducing the risk of gastric irritation.
Active Ingredients Enteric Coated Pantoprazole Sodium :
- Pantoprazole Sodium: Pantoprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach. It helps to alleviate symptoms and promote healing of acid-related disorders such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Domperidone: Domperidone is a dopamine receptor antagonist that increases gastrointestinal motility and helps to improve the movement of food through the stomach and intestines. Use to treat conditions like gastroparesis, nausea, vomiting, and other symptoms associated with delayed gastric emptying.
Mechanism of Action:
- Pantoprazole Sodium: Pantoprazole blocks the final step in the secretion of gastric acid by inhibiting the activity of the proton pump (H+/K+-ATPase) in the parietal cells of the stomach. This action leads to a decrease in the production of stomach acid, reducing acidity and providing relief from acid-related symptoms.
- Domperidone: Domperidone acts on the dopamine receptors in the gut and the brain’s chemoreceptor trigger zone (CTZ). By blocking these receptors, it increases the motility of the gastrointestinal tract, facilitating the movement of food and preventing nausea and vomiting.
Indications:
Enteric Coated Pantoprazole Sodium & Sustained Release Domperidone Capsule is indicated for the management of the following conditions:
- Gastroesophageal Reflux Disease (GERD): To relieve symptoms such as heartburn, acid regurgitation, and chest pain caused by excessive stomach acid.
- Peptic Ulcers: For the treatment of duodenal and gastric ulcers, reducing the risk of ulcer recurrence.
- Zollinger-Ellison Syndrome: To control excessive gastric acid production in patients with this rare condition.
- Gastroparesis: To improve stomach emptying and reduce symptoms like nausea and vomiting associated with delayed gastric emptying.
Dosage and Administration:
The dosage and administration of Enteric Coated Pantoprazole Sodium & Sustained Release Domperidone Capsule may vary depending on the specific condition, patient’s age and medical history. It is essential to follow the prescribed dosage and instructions provided by the healthcare professional.
Precautions Enteric Coated Pantoprazole Sodium :
- This medication may interact with other drugs, so it is essential to inform the healthcare provider about any other medications .
- It may not be suitable for individuals with certain medical conditions, including liver or kidney problems, heart conditions, and allergies to the active ingredients.
- Pregnant or breastfeeding women should consult a doctor before using this medication.
- Alcohol consumption should be limited during treatment.
Side Effects Enteric Coated Pantoprazole Sodium :
Common side effects may include headache, dizziness, diarrhea, stomach pain, and nausea. Severe allergic reactions and other serious side effects are rare but may occur. If any unusual or severe symptoms occurs, take medical attention immediately.
Conclusion:
Enteric Coated Pantoprazole Sodium & Sustained Release Domperidone Capsule is a combination medication use to treat gastrointestinal disorders. It combines Pantoprazole Sodium, a proton pump inhibitor that reduces stomach acid production, and Domperidone, which enhances gastrointestinal motility. The enteric coating ensures proper drug release and targeted effects. Proper usage, as per the doctor’s instructions, can help manage GERD, peptic ulcers, gastroparesis, and related conditions effectively. However,
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